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All Journal Jurnal Kedokteran Syiah Kuala Jurnal Anestesi Perioperatif Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Mutiara Medika: Jurnal Kedokteran dan Kesehatan Majalah Kedokteran Sriwijaya Jurnal Keperawatan Sriwijaya Biomedical Journal of Indonesia Syntax Literate : Jurnal Ilmiah Indonesia Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan SRIWIJAYA JOURNAL OF MEDICINE Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Aisyah : Jurnal Ilmu Kesehatan Sriwijaya Journal of Surgery Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research

Legiran Legiran

Fakultas Kedokteran Universitas Sriwijaya

Author-ID : 600353

Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Effects of Neoadjuvant Fluorouracyl-Adriamycin- Cytoxan (FAC) Chemotherapy Response to CD4 + Serum Levels In Breast Cancer Ade Permana; Benny Kusuma; Nur Qodir; Legiran
Sriwijaya Journal of Surgery Vol. 1 No. 1 (2018): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Introduction. CD4+ T-helper has an important role in immune system modulation especially to maintain long-term anti tumor effect. CD4+ also serves to activate CD8+ for destroyed the tumor cells. It was expected there were role of immunity on tumor growth and response of breast cancer chemotherapy to CD4+ levels serum. Furthermore, this study was aimed to investigate the effects of neoadjuvant chemotherapy on CD4+ levels in patients with locally advanced breast cancer at General Hospital Dr. Mohammad Hoesin Palembang. Method. This study was a non-comparable clinical trial by looking at serum CD4+ levels in patients with locally advanced breast cancer before and after neoadjuvant chemotherapy. Results. Of the 30 subjects the subject age ranged from 33-66 years with an average of 45 years. There were 17 patients with contraception history (56.7%), 13 patients with family history of breast cancer (43.3%). From this study, it was obtained 23 patients with good chemotherapy response (76.7%) and there were 7 patients who had poor chemotherapy response after neoadjuvan chemotherapy (23.3%). Paired t-test analysis showed that there was a significant difference in mean CD4+ count before and after neoadjuvan chemotherapy. At the CD4+ level before chemotherapy 775.55 had a sensitivity of 60% and a specificity of 57% (cut of point). While CD4+ levels after chemotherapy 470.85 with sensitivity of 60% and specificity of 57%. Conclusion. CD4+ pre-chemotherapy examination had a sensitivity score of 60% and a specificity of 57% in predicting neoadjuvant chemotherapy response.

Revised Trauma Score (RTS) as a Mortality Predictor on Abdominal Trauma Ade Dian Anggraini; Efman EU Manawan; Legiran
Sriwijaya Journal of Surgery Vol. 1 No. 1 (2018): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Introduction: Trauma is a major health problem throughout the world. Trauma is the most common cause of death and the most common cause of disability in adults and young adults. Abdominal trauma accounts for 7-10% of all trauma sufferers and causes severe trauma. The purpose of this study was to determine the relationship between the Revised Trauma Score (RTS) to the mortality of abdominal trauma sufferers. Methods: This study was an observational analytic study with a retrospective design to assess the relationship between Revised Trauma Score (RTS) and mortality in abdominal trauma patients treated in the Emergency Department of RSUP DR. Mohammad Hoesin Palembang. Data collected were analyzed using SPSS-23 devices using the chi-square method and Mann Whitney Results: 144 abdominal trauma patients studied. The mean age was 28 Â± 11,340 years, 97.4% were male, 64.0% of patients had abdominal trauma. The average RTS value was 7.429 Â± 1,001. The mean value in the group of patients who died was 6.628 Â± 0.795 and the mean value of the RTS in the group of patients who did not die was 7.459 Â± 0.795. There was a significant relationship between RTS values â€‹â€‹and mortality in abdominal trauma patients (p = 0.0.03). Conclusion: the results of this study indicate that RTS is a meaningful assessment system in predicting death in abdominal trauma patients

Development of Scoring System for Prediction of Choledocholithiasis Danny Amos Tarigan; Hafid Komar; Legiran
Sriwijaya Journal of Surgery Vol. 1 No. 1 (2018): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Introduction. Gallstones (cholelithiasis) and gallbladder stones (choledocholithiasis) are still a public health problem because of the high incidence rate. Management of stones in common bile duct (CBD) is done with history taking about patient complaints and tracking patient history such as yellow appearance, physical examination, laboratory examination, and imaging examination before, during and after surgery. Of the many imaging assessment that can be done, in practice not all can be done because these tests are expensive, complicated, risk of morbidity and mortality. A scoring system that includes many parameters can be very useful for many surgeons to be able to assess the presence of gallbladder stones. Methods. The study was an analytic observational study with a cross sectional study design carried out in the digestive surgery polyclinic and the inpatient installation of Dr. Moh Husein general hospital, Palembang from September 2018 to May 2019. The sample of this study was all patients suspected of having gallbladder stones that met the inclusion and exclusion criteria. Results: Receiver operating characteristic (ROC) analysis of scoring on bile duct stone diagnosis had a cut-off of> 4 with a sensitivity value of 100% and a specificity of 75%. In the Fisher's Exact analysis test and it was found that the scoring had a significant relationship to the diagnosis of bile duct stones with an odd ratio (OR) value of 12.52. Conclusion. The use of a scoring system can predict the incidence of gallbladder stones.

Comparison of Hip Functional Value and Quality of Life Between Cemented and Uncemented Hip Arthroplasty Patients Fredy Ferdinand Carol; Wiria Aryanta; Legiran
Sriwijaya Journal of Surgery Vol. 1 No. 1 (2018): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Abstract Introduction. Hip arthroplasty is aimed to reduce pain and restore hip joint function. Until now, the most optimal method for fixation in Hip Arthroplasty is controversial. The purpose of this study was to analyze the comparison of hip functional value and quality of life between cemented and uncemented hip arthroplasty patients. Methods. This study used cross sectional design. Data were collected via medical record and SF-12 questionnaire and Oxford hip score in patients who have received hip arthroplasty at general hospital Dr. Moh. Hoesin Palembang. Results: There were 43 cases found, consisting of 28 cemented cases and 15 uncemented cases. The average age was 60.42 Â± 19.44 years with an age range of 24-88 years. 20 subjects (46.4%) and 23 subjects (53.5%) women. The most preoperative diagnosis was trauma / fracture (69.8%), followed by osteoarthritis (16.3%), osteonecrosis (4.7%). Previous normality tests have been done with the Sapiro-Wilk test and homogeneity test. A comparison of hip functional values â€‹â€‹between cemented and uncemented hip arthroplasty patients had a value of p = 0.76 (p <0.05) meaning there was no significant difference. Comparison of quality of life between cemented and uncemented hip arthroplasty patients has a value of p = 0.592 (p <0.05) which also means there is no significant difference. Conclusion: There was no difference in pelvic functional value and quality of life between cemented and uncemented hip arthroplasty patients.

Co-Authors Achmad Ridwan, Achmad Ade Dian Anggraini Ade Permana Bella Ria Astuti Benny Kusuma Bernhard Arianto Purba Chandra, Novy Rosalia Danny Amos Tarigan Diana Polania Efman EU Manawan Efrieni Yusuf Ferry Yusrizal Fitri Nurjanah Fredy Ferdinand Carol Hafid Komar Indah, Furqan Indrajaya, Taufik Indri Seta Septadina Kgs. M. Rosyidi Kms Yusuf Effendi M. Zalili Azis Martinova, Vera Mediarty Mega Sary Meirisa Rahma Pratiwi Mgs.Muhammad Irsan Saleh Muhammad Arma Muhammad David Riandy Muhammad Irsan Saleh Muhammad Reagan Mutiara Budi Azhar Nadya Aviodita Nedya Bellinawati Nur Qodir Nur Riviati, Nur Nurjanah, Fitri Precelia Fransiska Puspa Zuleika, Puspa Qodir, Nur Ridho Surya Putra Rizal Sanif Rizal Zainal Salni Sary, Mega Shafira Irmayati Sugiharto, Henry Suly Auline Rusminan Tri Suciati Wiria Aryanta Yusni Puspita

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